Gut Microbiota, a Key Factor Relating Diet and Inflammation with the Progression of Cognitive Impairment in Older People

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Submit Manuscript | http://medcraveonline.com Abbreviations: 5-HT: 5 Hydroxy Triptamine; AD: Alzheimer Disease; Aβ: Amyloid-β; Aβ 1-42 and Aβ 1-40: Shorter peptides of Aβ released during pathogenesis; ApoE: Apolipoprotein E; CI: Cognitive Impairment; CMV: Cytomegalovirus; CRP: C Reactive Protein; CSF: Cerebrospinal Fluid; CSN: Central Nervous System; DA: Dopamine; EBV Epstein-Barr Virus; GF: Germ Free; IBS: Irritable Bowel Byndrome; IL-6; Inter Leukin 6; IL-8: Inter Leukin8; MAMPS: Microbe Associated Molecular Patter NA: NorAdrenalin PET: Positron Emission Tomography; PPA: Precursor Protein Amyloi; p-tau: Phosphorylated Tau Protein; SCFA: Short Chain Fatty Acid; sLRP : Soluble Low Density Lipoprotein ReceptorRelated Protein-1; SPF: Specific Pathogen Free; sRAGE: Soluble Receptor for Advanced Glycation End Products; TNF-α: Tumor Necrosis factor Alpha

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تاریخ انتشار 2017